08/05/2010 ACHN-490 Overview: Web Conference

Hosted in August 2010 by J. Kevin Judice, CEO & CSO
 - Listen to a recording of the web conference (use password: 90215265, pop-up windows must be enabled in your browser)
 - Download a PDF of the presentation

07/30/2010 New aminoglycoside antibiotics
Paola Dozzo & Heinz E Moser
Expert Opin. Ther. Patents (2010) 20(10)
Access this publication at informahealthcare.com

04/10/2010 Ototoxic Potential of ACHN-490 Compared to Gentamicin and Amikacin in the Guinea Pig
CF Kostrub, DF Dolan, RA Altschuler, RL Tapp, TJ Baird, JA Boggs, JB Bruss
Achaogen Inc, MPI Research, Kresge Hearing Research Institute
ECCMID 2010, poster # P-1249

02/09/2010 Antistaphylococcal Activity of ACHN-490 Tested Alone and in Combination with Other Agents by Time-Kill Assay
Gengrong Lin, Lois M. Ednie, and Peter C. Appelbaum
Antimicrobial Agents and Chemotherapy, doi:10.1128/AAC.01350-09
Access this publication at aac.asm.org

10/01/2009 ACHN-490, a Neoglycoside with Potent In Vitro Activity against Multidrug-Resistant Klebsiella pneumoniae Isolates
Andrea Endimiani, Kristine M. Hujer, Andrea M. Hujer, Eliana S. Armstrong, Yuvraj Choudhary, James B. Aggen, and Robert A. Bonomo
Antimicrobial Agents and Chemotherapy, October 2009, p. 4504-4507, Vol. 53, No. 10
Access this publication at aac.asm.org

09/13/2009 Activity of the Neoglycoside ACHN-490 Against a Contemporary Collection of Clinical Isolates Including Antimicrobial-Resistant Strains
RN Jones, ES Armstrong, JB Aggen, DJ Biedenbach, GH Miller
JMI Laboratories, Achaogen Inc.
ICAAC 2009, poster # F1-846a

09/13/2009 Pharmacokinetics of the Novel Neoglycoside ACHN-490 in Mouse, Rat, and Dog
Robert T. Cass, Jenny V. McKinnell, Bo Xie, Dane E. Karr, Donald E. Schmidt Jr.
Achaogen, Inc.
ICAAC 2009, poster # F1-846

09/13/2009 In Vivo Efficacy of the Neoglycoside ACHN-490 Against Enterobacteriaceae and MRSA Pharmacokinetics of the Novel Neoglycoside ACHN-490 in Mouse, Rat, and Dog
Noe Reyes, James B. Aggen, Corwin F. Kostrub
Achaogen, Inc.
ICAAC 2009, poster # F1-845

09/13/2009 Activity of ACHN-490 in Combination with Daptomycin, Ceftobiprole, or Linezolid Against 25 methicillin-resistant Staphylococcus aureus by Synergy Time-kill
Gengrong Lin, Lois M. Ednie, Peter C. Appelbaum
Department of Pathology, Hershey Medical Center
ICAAC 2009, poster # F1-844

09/13/2009 Activity of ACHN-490 Against Complicated Urinary Tract Infection (cUTI) Pathogens From the United States (USA) and Europe (EU)
DJ Biedenbach, RN Jones, ES Armstrong, JB Aggen, GH Miller
JMI Laboratories, Achaogen Inc.
ICAAC 2009, poster # F1-843

09/13/2009 Activity of ACHN-490, a Novel Neoglycoside Antibiotic, Against Contemporary Gram-negative Clinical Isolates from Brooklyn, NY Hospitals
Claudiu Georgescu, Don-Antonio Martin, Simona Bratu, John Quale, David Landman
SUNY Downstate Medical Center
ICAAC 2009, poster # F1-842

09/13/2009 The Bactericidal Activity of the Neoglycoside ACHN-490 Against Aminoglycoside-Resistant Bacteria
Gary Zurenko, Douglas Stapert, Mary Knechtel, Nanette Nichols, Dean Shinabarger, Eliana S. Armstrong, James B. Aggen, Lee Ann Feeney, Aya Kubo, Rowena D. Matias, George H. Miller
Micromyx, Achaogen Inc.
ICAAC 2009, poster # F1-841

09/13/2009 Synthesis, Structure, and in vitro Activity of the Neoglycoside ACHN-490
James B. Aggen, Eliana S. Armstrong, Adam A. Goldblum, Paola Dozzo, Martin S. Linsell, Micah J. Gliedt, Darin J. Hildebrandt, Lee Ann Feeney,Aya Kubo, Rowena D. Matias, Sara Lopez, Marcela Gomez, Kenneth B. Wlasichuk, Raymond Diokno, George H. Miller, Heinz E. Moser
Achaogen, Inc.
ICAAC 2009, poster # F1-840

07/21/2009 Quantitative comparison of aminoglycoside nephrotoxicity in rats for effective screening and evaluation of new derivatives, and dosing rationales that minimise toxicity
C.F. Kostrub, R. Diokno, J. Aggen, G. Miller, K. Judice, P. Tulkens
Achaogen Inc., Université catholique de Louvain
ECCMID 2009 poster P 1979

07/21/2009 Surveying aminoglycoside-resistance mechanisms: a tool for the development of neoglycosides
E. Armstrong, D. Biedenbach, R. Jones, G. Miller
Achaogen Inc., JMI Laboratories
ECCMID 2009 poster P 643

07/21/2009 Ten-year trend in aminoglycoside resistance from a worldwide collection of Gram-negative pathogens (1998-2007)
D. Biedenbach, R. Jones, G. Miller, E. Armstrong
JMI Laboratories, Achaogen, Inc.
ECCMID 2009 poster P 636