Population Pharmacokinetics (PPK) of Plazomicin and Use of Therapeutic Drug Management (TDM) in Critically Ill Patients

Scott A. Van Wart, M.S., Ph.D.1, Julie D. Seroogy, B.S.2, Michael Trang, Pharm.D.1, Lynn E. Connolly, MD, PhD2, Christopher M. Rubino, Pharm.D.1, Adrian M. Jubb, MBChB, Ph.D., FRCPath2, Sujata Bhavnani, Pharm.D., M.S.1, Valerie Riddle, M.D., FACP3, Tomoyuki Mizuno, Ph.D.4, Alexander A. Vinks, Pharm.D., Ph.D., FCP4 and Alan Forrest, Pharm.D.1, (1)Institute for Clinical Pharmacodynamics, Schenectady, NY, (2)Achaogen Inc., South San Francisco, CA, (3)BioPharmAdvisors LLC, Bumpass, VA, (4)Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

IDWeek 2016

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Utility of Therapeutic Drug Management (TDM) in Managing Plazomicin Pharmacokinetic (PK) Variability in Patients with Infections due to Carbapenem-Resistant Enterobacteriaceae (CRE)

George Daikos, MD1, Spyros Zakynthinos, MD2, Apostolos Komnos, MD3, Maria Souli, MD PhD4, Eleni Antoniadou, MD5, Glykeria Vlachogianni, MD6, Nikolaos Kapravelos, MD7, Alisa Serio, PhD8, Julie Seroogy, MS8, Alex Smith, MS8, Adrian M. Jubb, MBChB, Ph.D., FRCPath8, Antonia Koutsoukou, MD9, Konstantinos Pontikis, MD9, Anna Skiada, MD1 and Epaminondas Zakynthinos, MD10, (1)University of Athens, Athens, Greece, (2)Evangelismos Hospital, Athens, Greece, (3)General Hospital, Larissa, Greece, (4)Attikon Hospital, Athens, Greece, (5)G. Genimatas Hospital, Thessaloniki, Greece, (6)Agios Dimitrios Hospital, Thessaloniki, Greece, (7)Georgios Papanikolaou Hospital, Thessaloniki, Greece, (8)Achaogen, South San Francisco, CA, (9)Sotiria Hospital, Athens, Greece, (10)University Hospital, Larissa, Greece

IDWeek 2016

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